Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | ACP3 | P15309 | 2/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787598 | 0.96 | MAPKAPK2 (0.43) | MAPKAPK2MEN1KMT2APOLBACP3 | |
| SCHEMBL7785121 | 0.94 | MAPKAPK2 (0.46) | MAPKAPK2MEN1KMT2APOLBACP3 | |
| SCHEMBL7787694 | 0.92 | KMT2A (0.41) | MAPKAPK2MEN1KMT2APOLBCNR1 | |
| SCHEMBL7784990 | 0.92 | POLB (0.46) | MAPKAPK2MEN1KMT2APOLBRAPGEF4 | |
| SCHEMBL7787635 | 0.91 | MEN1 (0.38) | MAPKAPK2MEN1KMT2APOLBACP3 | |
| SCHEMBL7785293 | 0.89 | MAPKAPK2 (0.40) | MAPKAPK2MEN1KMT2APOLBACP3 | |
| SCHEMBL7787853 | 0.89 | KMT2A (0.38) | MAPKAPK2MEN1KMT2APOLBACP3 | |
| SCHEMBL7780349 | 0.89 | MEN1 (0.38) | MAPKAPK2MEN1KMT2APOLBS1PR3 | |
| SCHEMBL7784926 | 0.89 | KMT2A (0.38) | MAPKAPK2MEN1KMT2APOLBACP3 | |
| SCHEMBL7784925 | 0.89 | ALDH1A1 (0.41) | MAPKAPK2MEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |