Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 2/20 | 0.40 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780316 | 0.90 | ACP3 (0.49) | ACP3ALDH1A1GAALMNACASR | |
| SCHEMBL7784989 | 0.90 | ACP3 (0.45) | ACP3ALDH1A1GAALMNACASR | |
| SCHEMBL7780421 | 0.89 | CASR (0.51) | ACP3ALDH1A1GAALMNACASR | |
| SCHEMBL27530316 | 0.85 | ALDH1A1 (0.50) | ACP3ALDH1A1GAALMNACASR | |
| SCHEMBL7785179 | 0.85 | CASR (0.42) | ACP3ALDH1A1GAALMNACASR | |
| SCHEMBL7780790 | 0.85 | ALDH1A1 (0.50) | ACP3ALDH1A1GAALMNACASR | |
| SCHEMBL7787542 | 0.85 | CASR (0.40) | ACP3ALDH1A1GAALMNACASR | |
| SCHEMBL7785107 | 0.85 | ALDH1A1 (0.50) | ACP3ALDH1A1GAALMNACASR | |
| SCHEMBL7780312 | 0.85 | ACP3 (0.41) | ACP3ALDH1A1GAALMNACASR | |
| SCHEMBL7780437 | 0.85 | KRAS (0.44) | ALDH1A1GAAKRASSOS1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |