Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784989 | 0.95 | ACP3 (0.45) | ACP3ALDH1A1CYP3A4ACHECA1 | |
| SCHEMBL7780316 | 0.92 | ACP3 (0.49) | ACP3ALDH1A1CYP3A4ACHECA1 | |
| SCHEMBL7780321 | 0.89 | KMT2A (0.48) | ACP3ALDH1A1CYP3A4ACHECA1 | |
| SCHEMBL7780421 | 0.88 | CASR (0.51) | ACP3ALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL7789123 | 0.88 | MEN1 (0.48) | ACP3ALDH1A1CYP3A4ACHECA1 | |
| SCHEMBL7787542 | 0.88 | CASR (0.40) | ACP3ALDH1A1CYP3A4ACHECA1 | |
| SCHEMBL7785107 | 0.85 | ALDH1A1 (0.50) | ACP3ALDH1A1CYP3A4MAPTKMT2A | |
| SCHEMBL7784919 | 0.85 | ACP3 (0.40) | ACP3ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL7785129 | 0.85 | ALDH1A1 (0.45) | ACP3ALDH1A1CYP3A4ACHECA1 | |
| SCHEMBL7785574 | 0.85 | ALDH1A1 (0.45) | ACP3ALDH1A1CYP3A4ACHECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| CN-1287117-A | Cyclobutene derivatives, preparation method and therapeutic use thereof | SANKYO CO (JP) | 2001-03-14 | — | — | CN | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |