Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.34 |
| ▸ | TUBB | P07437 | 5/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784893 | 0.89 | ALDH1A1 (0.34) | ALDH1A1LMNAGAACA1CA2 | |
| SCHEMBL7785112 | 0.84 | KMT2A (0.44) | ALDH1A1LMNAGAAMAPTKMT2A | |
| SCHEMBL7789422 | 0.84 | ABCB1 (0.40) | ALDH1A1LMNAGAAABCB1ABCC1 | |
| SCHEMBL7785536 | 0.83 | ALDH1A1 (0.39) | ALDH1A1LMNAGAACA1CA2 | |
| SCHEMBL27540176 | 0.83 | ALDH1A1 (0.39) | ALDH1A1LMNAGAACA1CA2 | |
| SCHEMBL7787498 | 0.83 | CA1 (0.34) | LMNAGAAABCB1ABCC1CA1 | |
| SCHEMBL7780319 | 0.79 | CYP2D6 (0.40) | ALDH1A1LMNAGAACA1CA2 | |
| SCHEMBL7785129 | 0.79 | ALDH1A1 (0.45) | ALDH1A1LMNAGAACA1CA2 | |
| SCHEMBL7785574 | 0.79 | ALDH1A1 (0.45) | ALDH1A1LMNAGAACA1CA2 | |
| SCHEMBL7795456 | 0.78 | CXCR2 (0.35) | ALDH1A1LMNAGAAABCB1ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| CN-1287117-A | Cyclobutene derivatives, preparation method and therapeutic use thereof | SANKYO CO (JP) | 2001-03-14 | — | — | CN | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |