SCHEMBL7784977

SCHEMBL7784977

CC(=O)c1cccc2c1[C]=CC2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
KDM4E B2RXH2 1/20 0.41
NOTUM Q6P988 1/20 0.36
DRD2 P14416 2/20 0.33
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
THRB P10828 1/20 0.31
HRH4 Q9H3N8 1/20 0.31
PARP1 P09874 4/20 0.31
CYP1A2 P05177 1/20 0.31
ADRA2A P08913 1/20 0.31
MAOA P21397 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7790844 0.71 LMNA (0.34) ALDH1A1HPGDKDM4EDRD2GAA
SCHEMBL3396949 0.67 ALDH1A1 (0.47) ALDH1A1HPGDKDM4EL3MBTL1THRB
SCHEMBL29573534 0.67 ALDH1A1 (0.47) ALDH1A1HPGDKDM4EL3MBTL1THRB
SCHEMBL13980589 0.66 ALDH1A1 (0.42) ALDH1A1HPGDKDM4ENOTUMDRD2
SCHEMBL10968334 0.64 HTR2B (0.59) ALDH1A1HPGDKDM4EDRD2CYP1A2
SCHEMBL3491774 0.64 NPC1 (0.59) ALDH1A1HPGDKDM4EDRD2SMN1; SMN2
SCHEMBL7790916 0.64 ALDH1A1 (0.45) ALDH1A1HPGDKDM4ENOTUMDRD2
SCHEMBL279655 0.63 ALDH1A1 (0.53) ALDH1A1HPGDKDM4EGAAMAPT
SCHEMBL31359858 0.63 BCL2L1 (0.52) ALDH1A1HPGDKDM4EL3MBTL1THRB
SCHEMBL11866503 0.63 ALDH1A1 (0.43) ALDH1A1HPGDKDM4ENOTUMDRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155698-A1 ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES Nitto Kasei Co., Ltd. (JP) 2001-11-21 EP disclosed