Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 3/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2488793 | 0.87 | NQO1 (0.74) | NQO1SMN1; SMN2LMNATSHRTDP1 | |
| SCHEMBL10708237 | 0.85 | CYP1A2 (0.50) | SMN1; SMN2LMNATSHRKDM4ELTA4H | |
| SCHEMBL7425137 | 0.85 | LMNA (0.53) | SMN1; SMN2LMNAKDM4EMAPTDHFR | |
| SCHEMBL21151 | 0.83 | — | — | |
| SCHEMBL15201648 | 0.81 | NQO1 (0.64) | NQO1SMN1; SMN2LMNATSHRTDP1 | |
| SCHEMBL3889599 | 0.81 | NQO1 (0.62) | NQO1SMN1; SMN2TSHRTDP1KDM4E | |
| SCHEMBL27389125 | 0.81 | NQO1 (0.62) | NQO1SMN1; SMN2TSHRTDP1KDM4E | |
| SCHEMBL3887440 | 0.81 | NQO1 (0.62) | NQO1SMN1; SMN2TSHRTDP1KDM4E | |
| SCHEMBL27588995 | 0.81 | NQO1 (0.62) | NQO1SMN1; SMN2TSHRTDP1KDM4E | |
| SCHEMBL27617296 | 0.81 | NQO1 (0.62) | NQO1SMN1; SMN2TSHRTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001521492-A | — | — | 2001-11-06 | — | — | JP | claimed |
| EP-0960106-A1 | 1-PHENYL-4-BENZYLPIPERAZINES: DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS (D4) | NEUROGEN CORPORATION (US) | 1999-12-01 | — | — | EP | claimed |
| WO-1998033784-A1 | 1-PHENYL-4-BENZYLPIPERAZINES: DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS (D4) | NEUROGEN CORPORATION (US) | 1998-08-06 | — | — | WO | claimed |
| EP-3371199-A1 | A COMPLEX OF A GLUCOPYRANOSYL DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2018-09-12 | — | — | EP | disclosed |
| CN-107641139-A | Crystal formation of Dapagliflozin intermediate and preparation method thereof | 江苏豪森药业集团有限公司 | 2018-01-30 | — | — | CN | disclosed |
| CN-107629097-A | The solid form and its application method of a kind of compound | 莱西肯医药有限公司 | 2018-01-26 | — | — | CN | disclosed |
| WO-2017088839-A1 | A COMPLEX OF A GLUCOPYRANOSYL DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-06-01 | — | — | WO | disclosed |
| WO-2016041470-A1 | SGLT-2 INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2016-03-24 | — | — | WO | disclosed |
| EP-2895490-A1 | GLUCOPYRANOSYL DERIVATIVES AND THEIR USES IN MEDICINE | Sunshine Lake Pharma Co., Ltd. (CN) | 2015-07-22 | — | — | EP | disclosed |
| WO-2015043511-A1 | GLUCOPYRANOSYL DERIVATIVES AND THEIR USES IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-04-02 | — | — | WO | disclosed |
| WO-2015043473-A1 | GLUCOPYRANOSYL DERIVATIVES AND THEIR USES IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-04-02 | — | — | WO | disclosed |
| CN-104098536-A | Synthetic method of dideoxy C-glycosidic SGLT2 (sodium-dependent glucose cotransporter 2) inhibitor and intermediate product of preparation method | TIANJIN INST PHARM RESEARCH | 2014-10-15 | — | — | CN | disclosed |