SCHEMBL10708237

SCHEMBL10708237

CCCCOc1ccc(Cc2cc[c]cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.50
CYP2D6 P10635 2/20 0.50
KDM4E B2RXH2 1/20 0.50
PDE4A P27815 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HIF1A Q16665 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
PKM P14618 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.47
LTA4H P09960 3/20 0.47
HTT P42858 2/20 0.46
TSHR P16473 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
NR5A1 Q13285 1/20 0.46
LMNA P02545 1/20 0.45
HSD17B10 Q99714 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7425137 0.93 LMNA (0.53) CYP1A2CYP2D6KDM4EPDE4ASMN1; SMN2
SCHEMBL2492282 0.88 CYP2D6 (0.59) CYP1A2CYP2D6KDM4EPDE4ASMN1; SMN2
SCHEMBL49992 0.86 LTA4H (0.55) CYP1A2CYP2D6SMN1; SMN2LTA4HTSHR
SCHEMBL7785329 0.85 NQO1 (0.56) CYP1A2CYP2D6KDM4ESMN1; SMN2LTA4H
SCHEMBL27649786 0.84 LTA4H (0.53) CYP1A2CYP2D6SMN1; SMN2L3MBTL1LTA4H
SCHEMBL28106770 0.84 LTA4H (0.53) CYP1A2CYP2D6SMN1; SMN2LTA4HTSHR
SCHEMBL9815735 0.84 APP (0.49) CYP1A2CYP2D6KDM4EPDE4ASMN1; SMN2
SCHEMBL27428800 0.82 L3MBTL1 (0.49) CYP1A2CYP2D6KDM4EPDE4ASMN1; SMN2
SCHEMBL2089077 0.81 LTA4H (0.66) CYP1A2CYP2D6LTA4HTSHRCYP2C9
SCHEMBL7440978 0.81 L3MBTL1 (0.69) CYP1A2CYP2D6L3MBTL1LTA4HHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0120717-B1 ANTHRAQUINONE DYES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THE DYES MITSUBISHI KASEI CORPORATION (JP) 1988-12-07 EP disclosed
US-4528113-A Anthraquinone dye and liquid crystal composition containing the dye MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1985-07-09 US disclosed
EP-0120717-A2 Anthraquinone dyes and liquid crystal compositions containing the dyes MITSUBISHI KASEI CORPORATION (JP) 1984-10-03 EP disclosed