SCHEMBL7785465

SCHEMBL7785465

O=C(O)Cc1cc2cccc(Cl)c2[nH]1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.51
AKR1B1 P15121 1/20 0.49
HRH4 Q9H3N8 1/20 0.47
CA12 O43570 1/20 0.45
CA9 Q16790 1/20 0.45
CAMK2A Q9UQM7 3/20 0.41
KDM4E B2RXH2 1/20 0.41
CDK1 P06493 1/20 0.40
CCNB1 P14635 1/20 0.40
DRD2 P14416 1/20 0.38
DRD3 P35462 1/20 0.38
PCSK9 Q8NBP7 1/20 0.38
THRA P10827 1/20 0.38
THRB P10828 1/20 0.38
AKR1B10 O60218 1/20 0.38
UGT1A9 O60656 1/20 0.38
TRPA1 O75762 1/20 0.38
ABCB11 O95342 1/20 0.38
MT-CO2 P00403 1/20 0.38
TTR P02766 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5694491 0.82 GRIN2D (0.51) DAOAKR1B1CAMK2AKDM4ETHRB
SCHEMBL28706901 0.82 GRIN2D (0.44) DAOAKR1B1KDM4ETHRBKMT2A
SCHEMBL27568957 0.81 NSD2 (0.54) DAOHRH4KDM4EKMT2A
SCHEMBL30297579 0.80 DAO (0.53) DAOAKR1B1HRH4CA12CA9
SCHEMBL25505990 0.80 DAO (0.53) DAOAKR1B1HRH4CA12CA9
SCHEMBL9756096 0.79 HRH4 (0.46) AKR1B1HRH4KDM4EPTGS2SIRT1
SCHEMBL1144741 0.78 HPGD (0.60) DAOHRH4CA12CA9KDM4E
SCHEMBL12829820 0.78 DAO (0.50) DAOAKR1B1HRH4CA12CA9
SCHEMBL11199718 0.77 MTNR1A (0.62) HRH4CA12CA9KDM4EDRD2
SCHEMBL28003928 0.76 DAO (0.49) DAOAKR1B1HRH4CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010034887-A1 Transformation of guar JORSBOE MORTEN (DK) 2001-10-25 US disclosed
US-6307127-B1 TRANSFORMATION, REGENERATION AND SELECTION OF LEGUMES OF GENUS CYAMOPSIS, IN PARTICULAR AGROBACTERIUM-MEDIATED TRANSFORMATION OF GUAR(CYAMOPSIS TETRAGONOLOBA) TO GENETICALLY MODIFIED PLANTS BY USE OF BETA-LACTAMASE INHIBITOR SULBACTAM DANISCO A/S (DK) 2001-10-23 US disclosed
EP-0766743-A2 TRANSFORMATION OF GUAR DANISCO A/S (DK) 1997-04-09 EP disclosed
WO-1995034667-A2 TRANSFORMATION OF GUAR DANISCO A/S (DK) 1995-12-21 WO disclosed