Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GPR17 | Q13304 | 3/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20570654 | 0.79 | RHEB (0.42) | HRH4SIRT1GRIN1KDM4EGRIN2D | |
| SCHEMBL7785465 | 0.79 | DAO (0.51) | HRH4SIRT1KDM4EAKR1B1PTGS2 | |
| SCHEMBL3274871 | 0.77 | HRH4 (0.56) | HRH4GRIN1KDM4EGRIN2DGRIN3B | |
| SCHEMBL24453860 | 0.77 | HRH4 (0.41) | HRH4SIRT1GRIN1KDM4EGRIN2D | |
| SCHEMBL1091709 | 0.74 | HRH4 (0.56) | HRH4GRIN1KDM4EGRIN2DGRIN3B | |
| SCHEMBL5097277 | 0.73 | SIRT1 (0.74) | HRH4SIRT1KDM4EALDH1A1 | |
| SCHEMBL3521517 | 0.73 | HRH4 (0.43) | HRH4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL9270023 | 0.72 | SIRT1 (0.47) | SIRT1GRIN1KDM4EGRIN2DGRIN3B | |
| SCHEMBL29062685 | 0.72 | HRH4 (0.55) | HRH4GRIN1KDM4EGRIN2DGRIN3B | |
| SCHEMBL5185975 | 0.71 | ALDH1A1 (0.39) | HRH4SIRT1KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0256128-B1 | INDOLEACETIC ACID DERIVATIVES AND USE THEREOF AS PLANT GROWTH REGULATORS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1991-11-06 | — | — | EP | disclosed |