Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.66 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 9/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 3/20 | 0.37 |
| ▸ | FPR2 | P25090 | 3/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7791581 | 0.94 | GHSR (0.67) | GHSRAGTR1XIAPTRPV1FPR1 | |
| SCHEMBL7791728 | 0.94 | GHSR (0.66) | GHSRAGTR1XIAPTRPV1FPR1 | |
| SCHEMBL7785927 | 0.93 | GHSR (0.65) | GHSRAGTR1XIAPFPR1FPR2 | |
| SCHEMBL7786112 | 0.91 | GHSR (0.57) | GHSRAGTR1XIAPFPR1FPR2 | |
| SCHEMBL7791697 | 0.91 | GHSR (0.66) | GHSRAGTR1XIAP | |
| SCHEMBL7794456 | 0.91 | GHSR (0.70) | GHSRAGTR1XIAPTRPV1FPR1 | |
| SCHEMBL7786005 | 0.90 | GHSR (0.82) | GHSRAGTR1XIAPTRPV1FPR1 | |
| SCHEMBL7785922 | 0.89 | GHSR (0.78) | GHSRAGTR1XIAPPTGER1PTGER3 | |
| SCHEMBL7791643 | 0.89 | GHSR (0.68) | GHSRAGTR1XIAPTRPV1FPR1 | |
| SCHEMBL7786102 | 0.88 | GHSR (0.64) | GHSRAGTR1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659179-B1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO INC (US) | 2001-11-21 | — | — | EP | claimed |
| EP-0659179-B1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO INC (US) | 2001-11-21 | — | — | EP | disclosed |