Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.66 |
| ▸ | XIAP | P98170 | 9/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795530 | 0.94 | GHSR (0.66) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL7791739 | 0.94 | GHSR (0.68) | GHSRXIAPAGTR1NPY1RDRD2 | |
| SCHEMBL7791744 | 0.93 | GHSR (0.65) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL7785922 | 0.91 | GHSR (0.78) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL7785552 | 0.91 | GHSR (0.66) | GHSRXIAPAGTR1 | |
| SCHEMBL7793136 | 0.91 | GHSR (0.57) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL7786102 | 0.90 | GHSR (0.64) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL7786017 | 0.90 | GHSR (0.64) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL7796016 | 0.90 | GHSR (0.72) | GHSRXIAPAGTR1NPY1RDRD2 | |
| SCHEMBL7791711 | 0.89 | GHSR (0.84) | GHSRXIAPAGTR1NPY1RDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659179-B1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO INC (US) | 2001-11-21 | — | — | EP | claimed |
| EP-0659179-B1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO INC (US) | 2001-11-21 | — | — | EP | disclosed |