Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.53 |
| ▸ | ITGAV | P06756 | 14/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.47 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.47 |
| ▸ | EEF2K | O00418 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.41 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.41 |
| ▸ | ITGA8 | P53708 | 1/20 | 0.41 |
| ▸ | OGT | O15294 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8357385 | 0.86 | ITGB3 (0.55) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL6798729 | 0.83 | ITGB3 (0.44) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7997106 | 0.81 | ITGB3 (0.70) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7856513 | 0.79 | ITGB3 (0.45) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL3835113 | 0.78 | HTR6 (0.57) | ITGB3ITGAVEEF2KALDH1A1ATM | |
| SCHEMBL2841846 | 0.73 | ITGB3 (0.59) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL6367424 | 0.73 | ITGB3 (0.61) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL6366667 | 0.73 | ITGB3 (0.60) | ITGB3ITGAVEEF2KALDH1A1ATM | |
| SCHEMBL7786198 | 0.71 | ITGB3 (0.49) | ITGB3ITGAVEEF2KALDH1A1ATM | |
| SCHEMBL2837308 | 0.71 | ITGB3 (0.53) | ITGB3ITGAVITGA2BITGB1ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| US-6291503-B1 | β-phenylalanine derivatives as integrin antagonists | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-18 | — | — | US | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |