Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 2/20 | 0.46 |
| ▸ | GHSR | Q92847 | 4/20 | 0.44 |
| ▸ | F7 | P08709 | 4/20 | 0.39 |
| ▸ | F3 | P13726 | 4/20 | 0.39 |
| ▸ | ACE | P12821 | 4/20 | 0.39 |
| ▸ | MME | P08473 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786108 | 0.94 | XIAP (0.47) | XIAPGHSRF7F3ACE | |
| SCHEMBL7791878 | 0.89 | GHSR (0.49) | XIAPGHSRF7F3ACE | |
| SCHEMBL7794457 | 0.88 | GHSR (0.57) | XIAPGHSRF7F3ACE | |
| SCHEMBL7794541 | 0.87 | GHSR (0.49) | XIAPGHSRF7F3ACE | |
| SCHEMBL7786012 | 0.87 | GHSR (0.59) | XIAPGHSRF7F3ACE | |
| SCHEMBL7786010 | 0.85 | GHSR (0.59) | XIAPGHSRAGTR1 | |
| SCHEMBL7791803 | 0.84 | XIAP (0.44) | XIAPGHSRF7F3ACE | |
| SCHEMBL7796037 | 0.84 | GHSR (0.51) | XIAPGHSRF7F3ACE | |
| SCHEMBL7795736 | 0.84 | XIAP (0.42) | XIAPGHSRF7F3ACE | |
| SCHEMBL7792504 | 0.84 | GHSR (0.60) | XIAPGHSRF7F3ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659179-B1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO INC (US) | 2001-11-21 | — | — | EP | claimed |
| EP-0659179-B1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO INC (US) | 2001-11-21 | — | — | EP | disclosed |