SCHEMBL7786047

SCHEMBL7786047

FC(F)(F)c1cc(Br)cc(C2CO2)c1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 2/20 0.39
NOTUM Q6P988 2/20 0.37
HTR2B P41595 2/20 0.35
CHRM2 P08172 1/20 0.35
DRD3 P35462 1/20 0.35
S1PR1 P21453 1/20 0.34
S1PR3 Q99500 1/20 0.34
TSHR P16473 1/20 0.33
P2RX4 Q99571 1/20 0.32
P2RX7 Q99572 1/20 0.32
ACP1 P24666 1/20 0.32
FFAR1 O14842 1/20 0.32
TACR1 P25103 1/20 0.31
TEAD1 P28347 1/20 0.31
HTR2C P28335 2/20 0.31
HTR2A P28223 1/20 0.31
TAS2R14 Q9NYV8 1/20 0.31
KDM1A O60341 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6494759 0.86 HTR1A (0.40) HTR1ANOTUMHTR2BCHRM2DRD3
SCHEMBL532105 0.86 HTR1A (0.40) HTR1ANOTUMHTR2BCHRM2DRD3
SCHEMBL15455996 0.80 HTR1A (0.38) HTR1ANOTUMHTR2BCHRM2DRD3
SCHEMBL7784236 0.80 TSHR (0.44) TSHRKDM1A
SCHEMBL7787372 0.79 FFAR1 (0.45) HTR1ANOTUMHTR2BCHRM2DRD3
SCHEMBL7786250 0.78 HTR1A (0.38) HTR1ANOTUMHTR2BCHRM2DRD3
SCHEMBL7784381 0.78 HTR1A (0.36) HTR1ANOTUMHTR2BCHRM2DRD3
SCHEMBL15516662 0.77 NOTUM (0.46) NOTUMS1PR1S1PR3P2RX4P2RX7
SCHEMBL15516981 0.75 HTR1A (0.35) HTR1ANOTUMS1PR1S1PR3TACR1
SCHEMBL10244139 0.75 HTR1A (0.35) HTR1ANOTUMS1PR1S1PR3P2RX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4655296-A1 CBL-B INHIBITORS Aurigene Oncology Limited (IN) 2025-12-03 EP disclosed
WO-2024156938-A1 CBL-B INHIBITORS ORION CORPORATION (FI) 2024-08-02 WO disclosed
EP-0735142-B1 Process for producing (R)-styrene oxides SUMIKA FINE CHEMICALS CO LTD (JP) 2001-10-24 EP disclosed
US-5717116-A TREATING A MIXTURE OF PHENYLHALOGENOMETHYLCARBINOLS WITH A LIPASE IN THE PRESENCE OF A CARBOXYLATE FOLLOWED BY CYCLIZATION WITH A BASE SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) 1998-02-10 US disclosed
EP-0735142-A2 Process for producing (R)-styrene oxides SUMIKA FINE CHEMICAL COMPANY, LTD. (JP) 1996-10-02 EP disclosed