Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.51 |
| ▸ | YAP1 | P46937 | 2/20 | 0.49 |
| ▸ | STS | P08842 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043443 | 0.88 | ALDH1A1 (0.69) | ALDH1A1MAPTMAPK1L3MBTL1HTT | |
| SCHEMBL7043474 | 0.86 | ALDH1A1 (0.60) | ALDH1A1MAPTMAPK1L3MBTL1HTT | |
| SCHEMBL7391868 | 0.83 | ALDH1A1 (0.67) | ALDH1A1MAPTMAPK1L3MBTL1HTT | |
| SCHEMBL17262543 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MAPTMAPK1L3MBTL1HTT | |
| SCHEMBL2709640 | 0.82 | ALDH1A1 (0.74) | ALDH1A1MAPTMAPK1L3MBTL1HTT | |
| SCHEMBL4247075 | 0.81 | ALDH1A1 (0.78) | ALDH1A1MAPTMAPK1L3MBTL1HTT | |
| SCHEMBL4239069 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPTMAPK1L3MBTL1HTT | |
| SCHEMBL23724092 | 0.80 | ALDH1A1 (0.62) | ALDH1A1MAPTMAPK1L3MBTL1HTT | |
| SCHEMBL2418581 | 0.79 | PRMT5 (0.68) | ALDH1A1L3MBTL1PRMT5YAP1STS | |
| SCHEMBL7385055 | 0.79 | PRMT5 (0.56) | ALDH1A1MAPTMAPK1L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251918-B1 | FOR THERAPY OF STROKE, CEREBRAL ISCHEMIA, HEAD TRAUMA, OR EPILEPSY | WARNER-LAMBERT COMPANY | 2001-06-26 | — | — | US | disclosed |