Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | RAB9A | P51151 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.55 |
| ▸ | STS | P08842 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.53 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17047823 | 0.92 | ALDH1A1 (0.64) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL14873930 | 0.92 | ALDH1A1 (0.64) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL13696775 | 0.92 | ALDH1A1 (0.64) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL7391868 | 0.89 | ALDH1A1 (0.67) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL17832684 | 0.88 | ALDH1A1 (0.73) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL17554400 | 0.88 | ALDH1A1 (0.77) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL4115820 | 0.88 | ALDH1A1 (0.77) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL10210061 | 0.88 | ALDH1A1 (0.79) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL3843999 | 0.87 | CCR5 (0.64) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL2873727 | 0.86 | ALDH1A1 (0.75) | ALDH1A1NPC1MAPTMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4722207-A1 | OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-04-08 | — | — | EP | disclosed |
| US-20250195699-A1 | Radiolabeled Mu Opioid Antagonist and Methods of Making and Using the Same | REGENTS OF THE UNIVERSITY OF MICHIGAN, C/O INNOVATION PARTNERSHIPS | 2025-06-19 | — | — | US | disclosed |
| CN-120136842-A | Indole piperidine compound and preparation method and application thereof | 江苏海洋大学 | 2025-06-13 | — | — | CN | disclosed |
| WO-2024245444-A1 | OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-12-05 | — | — | WO | disclosed |
| WO-2024140637-A1 | OXOISOINDOLINYL SUBSTITUTED PIPERIDINEDIONE DERIVATIVE AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-07-04 | — | — | WO | disclosed |
| US-20240131032-A1 | AN ACTIVITY-GUIDED MAP OF ELECTROPHILE-CYSTEINE INTERACTIONS IN PRIMARY HUMAN IMMUNE CELLS | THE SCRIPPS RESEARCH INSTITUTE | 2024-04-25 | — | — | US | disclosed |
| EP-3822262-B1 | MUSCARINIC AGONISTS | HEPTARES THERAPEUTICS LTD (GB) | 2024-03-27 | — | — | EP | disclosed |
| CN-113292485-B | Benzyl piperazine urea TRPV1 antagonizing and MOR agonizing double-target medicine and its prepn and application | 河南大学 | 2023-10-27 | — | — | CN | disclosed |
| EP-4262986-A1 | COMPOUNDS USEFUL AS T CELL ACTIVATORS | Gossamer Bio Services, Inc. (US) | 2023-10-25 | — | — | EP | disclosed |
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | WILLIAM MARSH RICE UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
| EP-1379504-A1 | BIPIPERIDINYL-DERIVATIVES AND THEIR USE AS CHEMOKINE RECEPTORS INHIBITORS | Novartis Pharma GmbH (AT) | 2004-01-14 | — | — | EP | disclosed |
| WO-2003086397-A1 | MEDICINE FOR TREATING CANCER | KOWA CO., LTD. (JP) | 2003-10-23 | — | — | WO | disclosed |
| US-6605620-B1 | Such as 4-(N-(4-Methoxyphenyl)-N-(3-(3,4,5-trimethoxy-phenyl)-benzoylamino)-1-((2 -(3,4,5-trimethoxyphenyl)pyridin-4-yl)-methyl)piperidine; treatment and prevention of cell adhesion or infiltration | KOWA CO., LTD. (JP) | 2003-08-12 | — | — | US | disclosed |
| EP-1308439-A1 | PROLINE DERIVATIVES AND USE THEREOF AS DRUGS | WELFIDE CORPORATION (JP) | 2003-05-07 | — | — | EP | disclosed |
| US-20030069276-A1 | Amino piperidine derivatives | F.HOFFMANN-LA ROCHE AG (CH) | 2003-04-10 | — | — | US | disclosed |
| WO-2002081449-A1 | BIPIPERIDINYL-DERIVATIVES AND THEIR USE AS CHEMOKINE RECEPTORS INHIBITORS | NOVARTIS AG (CH) | 2002-10-17 | — | — | WO | disclosed |
| WO-2002079186-A2 | AMINOPIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2002-10-10 | — | — | WO | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0828754-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038471-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1996-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240131032-A1 | AN ACTIVITY-GUIDED MAP OF ELECTROPHILE-CYSTEINE INTERACTIONS IN PRIMARY HUMAN IMMUNE CELLS | GSTK1, GSTA2, GSTA1 | ALDH1A1 1423/4885NPC1 596/4885MAPT 4158/4885 |
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | PNMT, NCL, NPM1 | ALDH1A1 1805/4885NPC1 2535/4885MAPT 1551/4885 |
| US-20030069276-A1 | Amino piperidine derivatives | CCR5, CCR2, CXCR4 | ALDH1A1 1935/4885NPC1 1778/4885MAPT 4405/4885 |
| US-20250195699-A1 | Radiolabeled Mu Opioid Antagonist and Methods of Making and Using the Same | OPRM1, OPRK1, OPRL1 | ALDH1A1 2454/4885NPC1 1673/4885MAPT 2956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.