Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633929 | 0.94 | AR (0.88) | ARPGR | |
| Ru-58841 SCHEMBL1461459 | 0.90 | AR (1.00) | ARPGR | |
| Ru-58841 SCHEMBL29372187 | 0.90 | AR (1.00) | ARPGR | |
| SCHEMBL5579470 | 0.90 | AR (0.81) | ARPGR | |
| SCHEMBL4032680 | 0.90 | PGR (0.81) | ARPGR | |
| SCHEMBL3875038 | 0.89 | AR (0.75) | ARPGR | |
| SCHEMBL3873665 | 0.89 | AR (0.75) | ARPGR | |
| SCHEMBL3871464 | 0.89 | AR (0.75) | ARPGR | |
| SCHEMBL3873391 | 0.89 | AR (0.75) | ARPGR | |
| SCHEMBL630193 | 0.89 | AR (0.80) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869946-B1 | PHENYLIMIDAZOLIDINES AND USE THEREOF AS AN ANTIANDROGENIC AGENT | AVENTIS PHARMA SA (FR) | 2001-10-31 | — | — | EP | disclosed |
| US-6242611-B1 | SUCH AS 4-(4,4-DIMETHYL-2,5-DIOXO-3-(4-NITROOXYBUTYL) -1-IMIDAZOLIDINYL)-2-(TRIFLUOROMETHYL)BENZONITRILE USED AS ANTIANDROGENIC COMPOUNDS | HOECHST MARION ROUSSEL (FR) | 2001-06-05 | — | — | US | disclosed |
| EP-0869946-A1 | PHENYLIMIDAZOLIDINES AND USE THEREOF AS AN ANTIANDROGENIC AGENT | HOECHST MARION ROUSSEL (FR) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997023464-A1 | PHENYLIMIDAZOLIDINES AND USE THEREOF AS AN ANTIANDROGENIC AGENT | HOECHST MARION ROUSSEL (FR) | 1997-07-03 | — | — | WO | disclosed |