Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784512 | 0.80 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL7438590 | 0.77 | ALDH1A1 (0.38) | ALDH1A1THRBATML3MBTL1TSHR | |
| SCHEMBL6039837 | 0.76 | HPGD (0.36) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27802912 | 0.75 | ALDH1A1 (0.37) | ALDH1A1THRBATML3MBTL1TSHR | |
| SCHEMBL9013395 | 0.75 | ALDH1A1 (0.37) | ALDH1A1THRBATML3MBTL1TSHR | |
| SCHEMBL7441312 | 0.74 | GAA (0.39) | ALDH1A1THRBATML3MBTL1TSHR | |
| SCHEMBL8690515 | 0.72 | ALDH1A1 (0.35) | ALDH1A1THRBATML3MBTL1SMN1; SMN2 | |
| SCHEMBL9950000 | 0.71 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL8710504 | 0.69 | ALDH1A1 (0.61) | ALDH1A1THRBATML3MBTL1TSHR | |
| SCHEMBL675456 | 0.69 | ALDH1A1 (0.61) | ALDH1A1THRBATML3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823420-B1 | Substituted vinylurea derivatives and their use as ACAT inhibitors | SS PHARMACEUTICAL CO (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5866609-A | PROPHYLACTIC AND THERAPEUTIC AGENTS FOR ARTERIOSCLEROSIS. | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0823420-A2 | Substituted vinylurea derivatives and their use as ACAT inhibitors | SS PHARMACEUTICAL CO., LTD. (JP) | 1998-02-11 | — | — | EP | disclosed |