SCHEMBL7784512

SCHEMBL7784512

COC(=O)N([C]=O)N1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7786237 0.80 ALDH1A1 (0.38) ALDH1A1
SCHEMBL6039837 0.80 HPGD (0.36) ALDH1A1
SCHEMBL7779532 0.80 TSHR (0.30)
SCHEMBL7786577 0.78 SMN1; SMN2 (0.37) ALDH1A1TDP1
SCHEMBL9950000 0.75 ALDH1A1 (0.32) ALDH1A1
SCHEMBL27823606 0.72 ALDH1A1 (0.32) ALDH1A1TDP1
SCHEMBL9435862 0.67 TDP1 (0.35) ALDH1A1TDP1
SCHEMBL1851133 0.63
SCHEMBL7730984 0.62
SCHEMBL9651145 0.61 LIPE (0.50) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823420-B1 Substituted vinylurea derivatives and their use as ACAT inhibitors SS PHARMACEUTICAL CO (JP) 2001-10-24 EP disclosed
US-5866609-A PROPHYLACTIC AND THERAPEUTIC AGENTS FOR ARTERIOSCLEROSIS. SS PHARMACEUTICAL CO., LTD. (JP) 1999-02-02 US disclosed
EP-0823420-A2 Substituted vinylurea derivatives and their use as ACAT inhibitors SS PHARMACEUTICAL CO., LTD. (JP) 1998-02-11 EP disclosed