Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782879 | 0.92 | APEX1 (0.38) | PTGS2KDM4EALDH1A1GAACNR1 | |
| SCHEMBL7782871 | 0.91 | ALDH1A1 (0.38) | PTGS2KDM4EALDH1A1GAACNR1 | |
| SCHEMBL7784877 | 0.83 | ALDH1A1 (0.39) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL7786278 | 0.81 | GRM5 (0.33) | GRM5PTGS2KDM4EALDH1A1TP53 | |
| SCHEMBL7782850 | 0.77 | EGFR (0.33) | KDM4EALDH1A1GAACNR1 | |
| SCHEMBL7785839 | 0.76 | MAOA (0.36) | KDM4EALDH1A1GAACNR1MEN1 | |
| SCHEMBL7784924 | 0.73 | MAPT (0.39) | ALDH1A1GAAS1PR1CHRNA7MEN1 | |
| SCHEMBL8532395 | 0.72 | KDM4E (0.38) | KDM4EALDH1A1GAATP53CNR1 | |
| Hydrochloric Acid SCHEMBL28752946 | 0.71 | KDM4E (0.37) | KDM4EALDH1A1GAATP53CNR1 | |
| SCHEMBL7784737 | 0.69 | MAOA (0.42) | KDM4EALDH1A1GAACNR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |