Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786001 | 0.70 | KIF18A (0.46) | MAPK1TSHRMAPTMEN1KMT2A | |
| SCHEMBL7786212 | 0.70 | PDE7A (0.45) | MAPK1TSHRMAPTMEN1KMT2A | |
| SCHEMBL23507272 | 0.70 | TSHR (0.49) | MAPK1TSHRMAPTMEN1KMT2A | |
| SCHEMBL8665042 | 0.69 | TSHR (0.37) | MAPK1TSHRMAPTMEN1KMT2A | |
| SCHEMBL10451346 | 0.68 | TDP1 (0.50) | MAPK1TSHRMAPTMEN1KMT2A | |
| SCHEMBL10740644 | 0.68 | TSHR (0.39) | MAPK1TSHRMAPTMEN1KMT2A | |
| SCHEMBL8666107 | 0.68 | EPAS1 (0.40) | MAPK1TSHRMAPTMEN1KMT2A | |
| SCHEMBL7782705 | 0.67 | MAPK1 (0.44) | MAPK1TSHRMAPTMEN1KMT2A | |
| SCHEMBL7778214 | 0.66 | TDP1 (0.44) | MAPK1TSHRMAPTMEN1KMT2A | |
| SCHEMBL197577 | 0.65 | CYP1A2 (0.48) | MAPK1MEN1KMT2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |