Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 7/20 | 0.45 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP7 | Q93009 | 1/20 | 0.43 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778214 | 0.91 | TDP1 (0.44) | PDE7APDE7BMEN1KMT2AUSP7 | |
| SCHEMBL8665042 | 0.81 | TSHR (0.37) | PDE7APDE7BMEN1KMT2ATDP1 | |
| SCHEMBL7784803 | 0.77 | VCAM1 (0.43) | PDE7AMEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL7786001 | 0.71 | KIF18A (0.46) | MEN1KMT2ATSHRMAPK1POLB | |
| SCHEMBL7782881 | 0.71 | MAOA (0.51) | MEN1KMT2ATDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7786339 | 0.70 | MAPK1 (0.38) | PDE7APDE7BMEN1KMT2AUSP7 | |
| SCHEMBL23507204 | 0.69 | PDE7A (0.58) | PDE7APDE7BMEN1KMT2AUSP7 | |
| SCHEMBL4963975 | 0.69 | PDE7A (0.82) | PDE7APDE7BMEN1KMT2APDE4B | |
| SCHEMBL8666107 | 0.69 | EPAS1 (0.40) | MEN1KMT2ATDP1L3MBTL1TSHR | |
| SCHEMBL7782705 | 0.68 | MAPK1 (0.44) | MEN1KMT2ATDP1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5817691-A | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0801058-A1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | American Cyanamid Company (US) | 1997-10-15 | — | — | EP | disclosed |