SCHEMBL7786381

SCHEMBL7786381

C=Cc1cccc(C(=C)c2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
TDP1 Q9NUW8 2/20 0.45
TP53 P04637 1/20 0.45
KDR P35968 2/20 0.43
CHEK1 O14757 1/20 0.43
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
UNG P13051 1/20 0.41
AKT1 P31749 1/20 0.38
PTGS2 P35354 1/20 0.37
TTR P02766 1/20 0.36
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MAOB P27338 2/20 0.34
HDAC8 Q9BY41 1/20 0.34
AKR1C1 Q04828 1/20 0.34
PLIN1 O60240 1/20 0.34
LMNA P02545 1/20 0.34
BCHE P06276 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL6443572 0.87 ALDH1A1 (0.67) ALDH1A1TSHRTDP1TP53KDR
Styrene SCHEMBL28371715 0.85 ALDH1A1 (0.64) ALDH1A1TSHRTDP1TP53KDR
SCHEMBL17529236 0.83 TP53 (0.48) ALDH1A1TSHRTDP1TP53MEN1
SCHEMBL1745723 0.82 UNG (0.63) ALDH1A1TDP1KDRCHEK1MEN1
SCHEMBL8383017 0.81 ALDH1A1 (0.56) ALDH1A1TSHRTDP1KDRCHEK1
SCHEMBL814654 0.80 MEN1 (0.52) ALDH1A1TSHRTDP1KDRCHEK1
SCHEMBL10591564 0.79 TDP1 (0.38) ALDH1A1TSHRTDP1TP53KDR
SCHEMBL1941954 0.78 ATM (0.63) ALDH1A1TSHRTDP1MEN1KMT2A
SCHEMBL30502883 0.78 ATM (0.63) ALDH1A1TSHRTDP1MEN1KMT2A
SCHEMBL21811989 0.78 MEN1 (0.50) ALDH1A1TSHRTDP1KDRCHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0311689-B1 PROCESS FOR SELECTIVELY MONOHYDROFORMYLATING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1992-06-10 EP claimed
EP-0304495-B1 PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1992-05-27 EP claimed
EP-0282066-B1 (PHENYLETHENYL) PHENYLPROPIONALDEHYDE AND METHOD FOR PRODUCING (BENZOYLPHENYL) PROPIONIC ACID USING THE SAME NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1992-05-27 EP claimed
EP-0282065-B1 (PHENYLETHENYL) PHENYLPROPIONIC ACID AND ITS ESTER, AND METHOD FOR PRODUCING (BENZOYLPHENYL) PROPIONIC ACID OR ITS ESTER NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1992-05-27 EP claimed
EP-0282063-B1 1-(3-VINYLPHENYL)-1-PHENYL-HYDROCARBONS AND METHOD FOR PRODUCING THE SAME NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-10-16 EP claimed
US-4982007-A CARBONYLATION CATALYST NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-01-01 US claimed
US-4908473-A Reacting a (1-arylethenyl)vinylbenzene with carbon monoxide and water or alcohol in the presence of carbonylation catalyst NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1990-03-13 US claimed
US-4889952-A (Phenylethenyl) phenylpropionaldehyde and method for producing (benzolyphenyl) propionic acid using the same NIPPON PETROCHEMICAL COMPANY, LTD. (JP) 1989-12-26 US claimed
EP-0311689-A1 PROCESS FOR SELECTIVELY MONOHYDROFORMYLATING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-04-19 EP claimed
EP-0304495-A1 PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-03-01 EP claimed
EP-0282063-A1 1-(3-Vinylphenyl)-1-phenyl-hydrocarbons and method for producing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-09-14 EP claimed
EP-0282065-A2 (Phenylethenyl) phenylpropionic acid and its ester, and method for producing (benzoylphenyl) propionic acid or its ester NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-09-14 EP claimed
EP-0282066-A2 (Phenylethenyl) phenylpropionaldehyde and method for producing (benzoylphenyl) propionic acid using the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-09-14 EP claimed
JP-63233945-A None JP disclosed
JP-63233948-A None JP disclosed
JP-63233933-A None JP disclosed
EP-0282065-A2 (Phenylethenyl) phenylpropionic acid and its ester, and method for producing (benzoylphenyl) propionic acid or its ester NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-09-14 EP disclosed
EP-0282063-A1 1-(3-Vinylphenyl)-1-phenyl-hydrocarbons and method for producing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-09-14 EP disclosed
EP-0282066-A2 (Phenylethenyl) phenylpropionaldehyde and method for producing (benzoylphenyl) propionic acid using the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-09-14 EP disclosed
EP-0282063-A1 1-(3-Vinylphenyl)-1-phenyl-hydrocarbons and method for producing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-09-14 EP disclosed