⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetaldehyde SCHEMBL11327777 | 0.91 | — | — | |
| SCHEMBL11210418 | 0.82 | — | — | |
| SCHEMBL28581842 | 0.82 | CA2 (0.34) | — | |
| SCHEMBL1938236 | 0.80 | — | — | |
| SCHEMBL3169950 | 0.78 | — | — | |
| SCHEMBL9691386 | 0.78 | TSHR (0.36) | — | |
| SCHEMBL11319609 | 0.74 | LPAR3 (0.30) | — | |
| SCHEMBL7773058 | 0.74 | LPAR3 (0.30) | — | |
| SCHEMBL310640 | 0.74 | — | — | |
| SCHEMBL12461685 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 425 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10919900-B2 | Aryl hydrocarbon receptor antagonists and uses thereof | Magenta Therapeutics Inc. (US) | 2021-02-16 | — | — | US | claimed |
| EP-3321262-B1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2021-01-13 | — | — | EP | claimed |
| CN-106349217-B | Serine/threonine kinase inhibitors | 阵列生物制药公司 | 2020-08-28 | — | — | CN | claimed |
| EP-3652174-A1 | TAM KINASE INHIBITORS | Syros Pharmaceuticals, Inc. (US) | 2020-05-20 | — | — | EP | claimed |
| US-20200123161-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND USES THEREOF | EDIGENE BIOTECHNOLOGY, INC. (CN) | 2020-04-23 | — | — | US | claimed |
| US-10457683-B2 | Aryl hydrocarbon receptor antagonists and uses thereof | Magenta Therapeutics Inc. (US) | 2019-10-29 | — | — | US | claimed |
| US-10351572-B2 | Aryl hydrocarbon receptor antagonists and uses thereof | Magenta Therapeutics Inc. (US) | 2019-07-16 | — | — | US | claimed |
| US-20190177330-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND USES THEREOF | EDIGENE BIOTECHNOLOGY, INC. (CN) | 2019-06-13 | — | — | US | claimed |
| WO-2019014513-A1 | TAM KINASE INHIBITORS | SYROS PHARMACEUTICALS, INC. (US) | 2019-01-17 | — | — | WO | claimed |
| US-10154995-B2 | Serine/threonine kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2018-12-18 | — | — | US | claimed |
| EP-0640142-B1 | PROCESS FOR PRODUCTION OF AVERMECTINS AND CULTURES THEREFOR | PFIZER (US) | 1998-05-20 | — | — | EP | claimed |
| US-5576199-A | CULTURE OF STREPTOMYCES UNDER AEROBIC CONDITIONS IN NUTRIENTS | PFIZER INC. (US) | 1996-11-19 | — | — | US | claimed |
| EP-0276103-B1 | Process for production of B avermectins and cultures therefor | PFIZER (US) | 1993-10-20 | — | — | EP | claimed |
| EP-0284176-B1 | PROCESS FOR PRODUCTION OF AVERMECTINS AND CULTURES THEREFOR | PFIZER INC. (US) | 1993-08-25 | — | — | EP | claimed |
| EP-0313297-B1 | PROCESS FOR PRODUCTION OF AVERMECTIN AGLYCONES AND CULTURES THEREFOR | PFIZER INC. (US) | 1993-05-19 | — | — | EP | claimed |
| EP-0276131-B1 | NON-NATURAL DEMETHYLAVERMECTINS AND PROCESS THEREFOR | PFIZER INC. (US) | 1993-04-07 | — | — | EP | claimed |
| EP-0313297-A2 | Process for production of avermectin aglycones and cultures therefor | PFIZER INC. (US) | 1989-04-26 | — | — | EP | claimed |
| EP-0284176-A2 | Process for production of avermectins and cultures therefor | PFIZER INC. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0276103-A2 | Process for production of B avermectins and cultures therefor | PFIZER INC. (US) | 1988-07-27 | — | — | EP | claimed |
| EP-0276131-A2 | Non-natural demethylavermectins and process therefor | PFIZER INC. (US) | 1988-07-27 | — | — | EP | claimed |