Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL5471887 | 0.84 | CYP2C19 (0.40) | CYP2C19NPSR1HTTMEN1KMT2A | |
| Styrene SCHEMBL1762174 | 0.83 | CYP2C19 (0.42) | CYP2C19NPSR1HTTMEN1KMT2A | |
| Styrene SCHEMBL892493 | 0.82 | CYP2C19 (0.41) | CYP2C19NPSR1HTTMEN1KMT2A | |
| SCHEMBL18978908 | 0.82 | TDP1 (0.40) | CYP2C19HTTMEN1KMT2AKDM4E | |
| SCHEMBL8144058 | 0.81 | TDP1 (0.41) | CYP2C19HTTMEN1KMT2AKDM4E | |
| SCHEMBL10906591 | 0.79 | TSHR (0.43) | HTTKDM4ETDP1 | |
| SCHEMBL5420419 | 0.78 | HTT (0.42) | CYP2C19NPSR1HTTMEN1KMT2A | |
| SCHEMBL19064565 | 0.78 | ALDH1A1 (0.38) | MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL10905439 | 0.77 | TSHR (0.41) | HTTKDM4ETDP1 | |
| SCHEMBL5174696 | 0.77 | TSHR (0.41) | HTTKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0868460-B1 | COATING CONTAINING ACRYLOSILANE POLYMER TO IMPROVE MAR AND ACID ETCH RESISTANCE | DU PONT (US) | 2001-11-07 | — | — | EP | disclosed |
| EP-0868460-A1 | COATING CONTAINING ACRYLOSILANE POLYMER TO IMPROVE MAR AND ACID ETCH RESISTANCE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-10-07 | — | — | EP | disclosed |
| US-5684084-A | AUTOMOBILE FINISHES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-11-04 | — | — | US | disclosed |
| WO-1997022647-A1 | COATING CONTAINING ACRYLOSILANE POLYMER TO IMPROVE MAR AND ACID ETCH RESISTANCE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-06-26 | — | — | WO | disclosed |