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Styrene

Styrene

SCHEMBL1762174

C=C(C)C(=O)OC.C=C(C)C(=O)OCCO.C=C(CC)C(=O)OCCCCCC.C=CC(=O)OC1CC2CCC1(C)C2(C)C.C=CC(=O)OCCCC.C=Cc1ccccc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2C19 P33261 1/20 0.42
▸ MAPT P10636 6/20 0.37
▸ NPSR1 Q6W5P4 4/20 0.37
▸ HTT P42858 4/20 0.37
▸ KMT2A Q03164 4/20 0.37
▸ LMNA P02545 3/20 0.37
▸ MEN1 O00255 3/20 0.37
▸ KDM4E B2RXH2 2/20 0.37
▸ MAPK1 P28482 3/20 0.35
▸ PLA2G1B P04054 1/20 0.35
▸ RAD52 P43351 1/20 0.35
▸ ATG4B Q9Y4P1 1/20 0.35
▸ GAA P10253 1/20 0.34
▸ XBP1 P17861 1/20 0.34
▸ ELANE P08246 2/20 0.34
▸ CYP19A1 P11511 2/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ CNR1 P21554 2/20 0.31
▸ CNR2 P34972 2/20 0.31
▸ TSHR P16473 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL892493 0.94 CYP2C19 (0.41) CYP2C19MAPTNPSR1HTTKMT2A
Styrene SCHEMBL5471887 0.89 CYP2C19 (0.40) CYP2C19MAPTNPSR1HTTKMT2A
Styrene SCHEMBL16822370 0.87 CYP2C19 (0.39) CYP2C19MAPTNPSR1HTTKMT2A
SCHEMBL644546 0.87 LMNA (0.47) CYP2C19MAPTNPSR1HTTKMT2A
SCHEMBL5420419 0.83 HTT (0.42) CYP2C19MAPTNPSR1HTTKMT2A
SCHEMBL7786704 0.83 CYP2C19 (0.41) CYP2C19MAPTNPSR1HTTKMT2A
SCHEMBL645678 0.82 LMNA (0.48) CYP2C19MAPTNPSR1HTTKMT2A
Methacrylic Acid SCHEMBL7080056 0.81 LMNA (0.49) CYP2C19MAPTNPSR1HTTKMT2A
Styrene SCHEMBL7210426 0.81 TSHR (0.44) HTTLMNAKDM4ESMN1; SMN2TSHR
SCHEMBL644917 0.81 HTT (0.44) CYP2C19MAPTNPSR1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8357456-B2 Rapid drying lacquers E I DU PONT DE NEMOURS AND COMPANY (US) 2013-01-22 — — US disclosed
US-20110117379-A1 RAPID DRYING LACQUERS E.I.DU PONT DE NEMOURS AND COMPANY (US) 2011-05-19 — — US disclosed
EP-2231797-A2 RAPID DRYING LACQUERS E. I. du Pont de Nemours and Company (US) 2010-09-29 — — EP disclosed
WO-2009086267-A9 RAPID DRYING LACQUERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-11-26 — — WO disclosed
WO-2009086267-A2 RAPID DRYING LACQUERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-07-09 — — WO disclosed