Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP1 | P07148 | 2/20 | 0.49 |
| ▸ | PKLR | P30613 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786970 | 1.00 | FABP1 (0.49) | FABP1PKLRALDH1A1GAAMEN1 | |
| SCHEMBL7782131 | 0.91 | MEN1 (0.57) | FABP1PKLRALDH1A1GAAMEN1 | |
| SCHEMBL7782132 | 0.91 | MEN1 (0.57) | FABP1PKLRALDH1A1GAAMEN1 | |
| SCHEMBL7787796 | 0.88 | ALDH1A1 (0.52) | FABP1PKLRALDH1A1GAAMEN1 | |
| SCHEMBL7789833 | 0.86 | ALDH1A1 (0.50) | FABP1PKLRALDH1A1GAAMEN1 | |
| SCHEMBL7786996 | 0.86 | FABP1 (0.50) | FABP1PKLRALDH1A1GAAMEN1 | |
| SCHEMBL7786993 | 0.86 | FABP1 (0.50) | FABP1PKLRALDH1A1GAAMEN1 | |
| SCHEMBL7378076 | 0.82 | CAPN1 (0.53) | MEN1KMT2A | |
| SCHEMBL7782239 | 0.82 | CAPN1 (0.53) | MEN1KMT2A | |
| SCHEMBL7790039 | 0.81 | NAMPT (0.49) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |