Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | FABP1 | P07148 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | PKLR | P30613 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787796 | 0.93 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2APDE4BFABP1 | |
| SCHEMBL7782158 | 0.91 | MEN1 (0.61) | ALDH1A1MEN1KMT2AGAAPKLR | |
| SCHEMBL7786970 | 0.86 | FABP1 (0.49) | ALDH1A1MEN1KMT2APDE4BFABP1 | |
| SCHEMBL7786973 | 0.86 | FABP1 (0.49) | ALDH1A1MEN1KMT2APDE4BFABP1 | |
| SCHEMBL7791355 | 0.83 | MEN1 (0.63) | ALDH1A1MEN1KMT2AGAAKCNA5 | |
| SCHEMBL7782230 | 0.79 | AKR1C3 (0.50) | ALDH1A1MEN1KMT2AGAAPKLR | |
| SCHEMBL7782228 | 0.79 | AKR1C3 (0.50) | ALDH1A1MEN1KMT2AGAAPKLR | |
| SCHEMBL7388646 | 0.79 | MEN1 (0.49) | ALDH1A1MEN1KMT2APDE4BFABP1 | |
| SCHEMBL7686601 | 0.79 | TRPV1 (0.46) | ALDH1A1MEN1KMT2APDE4BFABP1 | |
| SCHEMBL7782132 | 0.77 | MEN1 (0.57) | ALDH1A1MEN1KMT2AFABP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |