SCHEMBL7786994 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	REN	P00797	7/20	0.39

▸	RXRA	P19793	2/20	0.35

▸	ALDH1A1	P00352	3/20	0.35

▸	POLB	P06746	2/20	0.35

▸	GAA	P10253	2/20	0.35

▸	MTNR1A	P48039	1/20	0.34

▸	MTNR1B	P49286	1/20	0.34

▸	SMN1; SMN2	Q16637	2/20	0.34

▸	CYP1A2	P05177	1/20	0.34

▸	CYP2C9	P11712	1/20	0.34

▸	CYP2C19	P33261	1/20	0.34

▸	USP2	O75604	1/20	0.34

▸	CYP3A4	P08684	2/20	0.33

▸	MEN1	O00255	2/20	0.33

▸	KMT2A	Q03164	2/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7606450	0.87	REN (0.44)	RENRXRAALDH1A1POLBGAA
SCHEMBL7601625	0.80	REN (0.49)	RENRXRAALDH1A1POLBGAA
SCHEMBL12354381	0.80	ALDH1A1 (0.41)	RENALDH1A1POLBGAAMTNR1A
SCHEMBL27822436	0.79	REN (0.39)	RENRXRAALDH1A1POLBGAA
SCHEMBL12353125	0.79	ALDH1A1 (0.39)	RENALDH1A1POLBGAASMN1; SMN2
SCHEMBL12353624	0.79	ALDH1A1 (0.51)	RENALDH1A1POLBGAASMN1; SMN2
SCHEMBL12353623	0.79	ALDH1A1 (0.40)	RENALDH1A1POLBGAASMN1; SMN2
SCHEMBL14747529	0.78	ALDH1A1 (0.38)	RENALDH1A1POLBGAASMN1; SMN2
SCHEMBL7601626	0.78	REN (0.36)	RENRXRAALDH1A1MTNR1AMTNR1B
SCHEMBL12354383	0.77	ALDH1A1 (0.39)	RENALDH1A1POLBGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2010150840-A1	N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE	大日本住友製薬株式会社 (JP)	2010-12-29	—	—	WO	disclosed