Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7778989 | 0.85 | — | — | |
| Iodide SCHEMBL27182228 | 0.82 | — | — | |
| Bromide SCHEMBL27182242 | 0.82 | — | — | |
| Fluoride Ion SCHEMBL27182304 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL27182238 | 0.76 | CYP11B1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL687758 | 0.76 | CYP19A1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL29565043 | 0.76 | CYP19A1 (0.32) | — | |
| Toluene SCHEMBL7806717 | 0.75 | LMNA (0.41) | — | |
| Iodide SCHEMBL27182235 | 0.73 | — | — | |
| Bromide SCHEMBL27182232 | 0.73 | HTR2A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0645401-B1 | Process for producing polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2001-12-05 | — | — | EP | claimed |
| US-5700886-A | Process for the preparation of polyolefins | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-23 | — | — | US | claimed |
| US-5696045-A | USING MIXTURE OF ZIRCONOCENE CATALYSTS | TARGOR GMBH (DE) | 1997-12-09 | — | — | US | claimed |
| US-6150481-A | CATALYTIC OLEFIN POLYMERIZATION WITH COORDINATION CATALYSTS | TARGOR GMBH (DE) | 2000-11-21 | — | — | US | disclosed |
| US-5700886-A | Process for the preparation of polyolefins | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-23 | — | — | US | disclosed |