Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19130508 | 0.79 | KDM1A (0.46) | KDM1AMAOBCASP6SIGMAR1TSHR | |
| SCHEMBL19124500 | 0.79 | KDM1A (0.46) | KDM1AMAOBCASP6SIGMAR1TSHR | |
| SCHEMBL15891592 | 0.79 | KDM1A (0.46) | KDM1AMAOBCASP6SIGMAR1TSHR | |
| SCHEMBL2150153 | 0.79 | SIGMAR1 (0.45) | KDM1AMAOBSIGMAR1TSHRALDH1A1 | |
| SCHEMBL7782464 | 0.76 | ESR2 (0.48) | KDM1AMAOBSIGMAR1 | |
| SCHEMBL31230954 | 0.75 | KDM1A (0.44) | KDM1AMAOBSIGMAR1TSHRALDH1A1 | |
| SCHEMBL11800619 | 0.75 | KDM1A (0.44) | KDM1AMAOBSIGMAR1TSHRALDH1A1 | |
| SCHEMBL8734058 | 0.74 | KDM1A (0.44) | KDM1AMAOBSIGMAR1TSHRALDH1A1 | |
| SCHEMBL29556714 | 0.74 | KDM1A (0.44) | KDM1AMAOBSIGMAR1TSHRALDH1A1 | |
| SCHEMBL7788015 | 0.73 | SIGMAR1 (0.51) | KDM1AMAOBSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010029286-A1 | Procatalysts, catalyst systems, and use in OLEFIN polymerization | EASTMAN CHEMICAL COMPANY, A CORP. OF DELAWARE | 2001-10-11 | — | — | US | disclosed |
| US-20010025005-A1 | Procatalysts, catalyst systems, and use in olefin polymerization | EASTMAN CHEMICAL COMPANY, A CORPORATION OF DELAWARE | 2001-09-27 | — | — | US | disclosed |
| WO-2001051527-A1 | PROCATALYSTS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |
| WO-2001051529-A1 | PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |