Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | EBP | Q15125 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782450 | 0.95 | SIGMAR1 (0.51) | SIGMAR1ESR2EBPKDM1ALMNA | |
| SCHEMBL7782520 | 0.93 | SIGMAR1 (0.54) | SIGMAR1ESR2EBPKDM1ALMNA | |
| SCHEMBL7788011 | 0.93 | SIGMAR1 (0.54) | SIGMAR1ESR2EBPKDM1ALMNA | |
| SCHEMBL7788022 | 0.93 | SIGMAR1 (0.54) | SIGMAR1ESR2EBPKDM1ALMNA | |
| SCHEMBL3296187 | 0.90 | SIGMAR1 (0.54) | SIGMAR1ESR2EBPKDM1A | |
| SCHEMBL7782464 | 0.89 | ESR2 (0.48) | SIGMAR1ESR2EBPKDM1ALMNA | |
| Ammonia Solution, Strong SCHEMBL27550700 | 0.87 | ESR2 (0.47) | SIGMAR1ESR2EBPKDM1ALMNA | |
| SCHEMBL28549243 | 0.83 | SIGMAR1 (0.56) | SIGMAR1EBPKDM1A | |
| SCHEMBL11198839 | 0.83 | SIGMAR1 (0.56) | SIGMAR1EBPKDM1A | |
| SCHEMBL28548755 | 0.83 | SIGMAR1 (0.56) | SIGMAR1EBPKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010029286-A1 | Procatalysts, catalyst systems, and use in OLEFIN polymerization | EASTMAN CHEMICAL COMPANY, A CORP. OF DELAWARE | 2001-10-11 | — | — | US | disclosed |
| US-20010025005-A1 | Procatalysts, catalyst systems, and use in olefin polymerization | EASTMAN CHEMICAL COMPANY, A CORPORATION OF DELAWARE | 2001-09-27 | — | — | US | disclosed |