SCHEMBL7787436

SCHEMBL7787436

CCCCCCCCO[Si](OCCCCCCCC)(OCCCCCCCC)OCCCCC1CO1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.68
TDP1 Q9NUW8 1/20 0.53
EPHX1 P07099 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.43
SPHK1 Q9NYA1 5/20 0.41
SPHK2 Q9NRA0 5/20 0.41
CYP1A2 P05177 2/20 0.38
ENPP2 Q13822 1/20 0.38
LPAR2 Q9HBW0 1/20 0.38
PRKD3 O94806 2/20 0.36
PRKCG P05129 2/20 0.36
PRKCB P05771 2/20 0.36
PRKCA P17252 2/20 0.36
PRKCH P24723 2/20 0.36
PRKCI P41743 2/20 0.36
PRKCE Q02156 2/20 0.36
PRKCQ Q04759 2/20 0.36
PRKCZ Q05513 2/20 0.36
PRKCD Q05655 2/20 0.36
PRKD1 Q15139 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7787430 1.00 ALDH1A1 (0.68) ALDH1A1TDP1EPHX1SMN1; SMN2SPHK1
SCHEMBL7786205 0.95 ALDH1A1 (0.59) ALDH1A1TDP1EPHX1SMN1; SMN2SPHK1
SCHEMBL27957417 0.91 ALDH1A1 (0.53) ALDH1A1TDP1EPHX1SMN1; SMN2SPHK1
SCHEMBL2227441 0.87 ALDH1A1 (0.48) ALDH1A1TDP1EPHX1SMN1; SMN2TSHR
SCHEMBL28975236 0.84 ALDH1A1 (0.48) ALDH1A1TDP1EPHX1SMN1; SMN2SPHK1
SCHEMBL11341291 0.83 ALDH1A1 (0.76) ALDH1A1TDP1EPHX1SMN1; SMN2SPHK1
SCHEMBL11358651 0.83 ALDH1A1 (0.76) ALDH1A1TDP1EPHX1SMN1; SMN2SPHK1
SCHEMBL11350272 0.83 ALDH1A1 (0.76) ALDH1A1TDP1EPHX1SMN1; SMN2SPHK1
SCHEMBL3619774 0.83 ALDH1A1 (0.76) ALDH1A1TDP1EPHX1SMN1; SMN2SPHK1
SCHEMBL10019014 0.83 ALDH1A1 (0.76) ALDH1A1TDP1EPHX1SMN1; SMN2SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0789053-B1 Stabiliser mixtures and their application in polycarbonates BAYER AG (DE) 2001-10-24 EP disclosed
US-5852138-A Stabilizer mixtures and their use in polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 1998-12-22 US disclosed
EP-0789053-A1 Stabiliser mixtures and their application in polycarbonates BAYER AG (DE) 1997-08-13 EP disclosed
EP-0507178-A2 Stabilization of high temperature deformation resistant polycarbonate BAYER AG (DE) 1992-10-07 EP disclosed
US-4375525-A Use of organic silicon compounds for stabilizing and brightening polycarbonates which are free from phosphites and free from boric acid esters BAYER AKTIENGESELLSCHAFT (DE) 1983-03-01 US disclosed
US-4342681-A Use of organic silicon compounds in combination with oxetane compounds, dioxanes or tetrahydrofuranes for stabilizing and brightening polycarbonates which are free from phosphites and free from boric acid esters BAYER AKTIENGESELLSCHAFT (DE) 1982-08-03 US disclosed
EP-0019217-A1 Use of organic silicium compounds in combination with oxetane compounds, dioxanes or tetrahydrofuranes for the stabilisation and brightening of polycarbonates free from phosphites and boric acid esters BAYER AG (DE) 1980-11-26 EP disclosed