SCHEMBL7786205

SCHEMBL7786205

CCCCO[Si](OCCCC)(OCCCC)OCCCCC1CO1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
SMN1; SMN2 Q16637 1/20 0.48
TDP1 Q9NUW8 1/20 0.46
EPHX1 P07099 1/20 0.41
TSHR P16473 1/20 0.36
SPHK1 Q9NYA1 5/20 0.36
SPHK2 Q9NRA0 5/20 0.36
ENPP2 Q13822 1/20 0.33
LPAR2 Q9HBW0 1/20 0.33
CYP1A2 P05177 2/20 0.32
PRKD3 O94806 1/20 0.31
PRKCG P05129 1/20 0.31
PRKCB P05771 1/20 0.31
PRKCA P17252 1/20 0.31
PRKCH P24723 1/20 0.31
PRKCI P41743 1/20 0.31
PRKCE Q02156 1/20 0.31
PRKCQ Q04759 1/20 0.31
PRKCZ Q05513 1/20 0.31
PRKCD Q05655 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7787430 0.95 ALDH1A1 (0.68) ALDH1A1SMN1; SMN2TDP1EPHX1TSHR
SCHEMBL7787436 0.95 ALDH1A1 (0.68) ALDH1A1SMN1; SMN2TDP1EPHX1TSHR
SCHEMBL27957417 0.93 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2TDP1EPHX1TSHR
SCHEMBL2227441 0.89 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2TDP1EPHX1TSHR
SCHEMBL1877887 0.83 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2TDP1EPHX1TSHR
SCHEMBL19125936 0.83 SMN1; SMN2 (0.60) ALDH1A1SMN1; SMN2TDP1TSHRENPP2
SCHEMBL3622865 0.82 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2TDP1EPHX1TSHR
SCHEMBL15508203 0.82 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2TDP1EPHX1TSHR
SCHEMBL10465672 0.82 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2TDP1EPHX1TSHR
SCHEMBL29653728 0.82 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2TDP1EPHX1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0789053-B1 Stabiliser mixtures and their application in polycarbonates BAYER AG (DE) 2001-10-24 EP disclosed
US-5852138-A Stabilizer mixtures and their use in polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 1998-12-22 US disclosed
EP-0789053-A1 Stabiliser mixtures and their application in polycarbonates BAYER AG (DE) 1997-08-13 EP disclosed
EP-0507178-A2 Stabilization of high temperature deformation resistant polycarbonate BAYER AG (DE) 1992-10-07 EP disclosed
US-4375525-A Use of organic silicon compounds for stabilizing and brightening polycarbonates which are free from phosphites and free from boric acid esters BAYER AKTIENGESELLSCHAFT (DE) 1983-03-01 US disclosed
US-4342681-A Use of organic silicon compounds in combination with oxetane compounds, dioxanes or tetrahydrofuranes for stabilizing and brightening polycarbonates which are free from phosphites and free from boric acid esters BAYER AKTIENGESELLSCHAFT (DE) 1982-08-03 US disclosed
EP-0019217-A1 Use of organic silicium compounds in combination with oxetane compounds, dioxanes or tetrahydrofuranes for the stabilisation and brightening of polycarbonates free from phosphites and boric acid esters BAYER AG (DE) 1980-11-26 EP disclosed