Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MMP14 | P50281 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7685023 | 0.92 | ALDH1A1 (0.61) | KDM4EL3MBTL1MCL1ALDH1A1HPGD | |
| SCHEMBL7684587 | 0.86 | KDM4E (0.64) | KDM4EL3MBTL1MCL1ALDH1A1HPGD | |
| SCHEMBL7689196 | 0.86 | KDM4E (0.64) | KDM4EMCL1ALDH1A1HPGDLMNA | |
| Bromide SCHEMBL7687716 | 0.86 | ALDH1A1 (0.50) | KDM4EL3MBTL1ALDH1A1LMNAMMP14 | |
| SCHEMBL7689285 | 0.83 | MAPT (0.51) | KDM4EL3MBTL1MCL1ALDH1A1LMNA | |
| SCHEMBL7691072 | 0.81 | KMT2A (0.62) | KDM4EL3MBTL1ALDH1A1HPGDLMNA | |
| SCHEMBL7685010 | 0.78 | ALDH1A1 (0.60) | KDM4EMCL1ALDH1A1HPGDLMNA | |
| SCHEMBL10908982 | 0.77 | MEN1 (0.64) | KDM4EL3MBTL1ALDH1A1HPGDLMNA | |
| SCHEMBL7683302 | 0.76 | MEN1 (0.58) | KDM4EL3MBTL1MCL1ALDH1A1HPGD | |
| SCHEMBL4066967 | 0.76 | EGLN1 (0.66) | KDM4EL3MBTL1ALDH1A1ADAMTS5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211376-B1 | HERPES VIRUS, CYTOMEGALO VIRUS, VARICELLA-ZOSTER VIRUS,EPSTEIN-BARR VIRUS | PHARMACIA & UPJOHN COMPANY | 2001-04-03 | — | — | US | claimed |
| US-6310211-B1 | ANTI-VIRAL ACTIVITY AGAINST HERPES VIRUS, CYTOMEGALOVIRUS. MANY OF THESE COMPOUNDS ARE ALSO ACTIVE AGAINST VARICELLA ZOSTER VIRUS, EPSTEIN-BARR VIRUS, HERPES SIMPLEX VIRUS AND HUMAN HERPES VIRUS TYPE 8 | PHARMACIA & UPJOHN COMPANY | 2001-10-30 | — | — | US | disclosed |
| US-6252080-B1 | HERPES, CYTOMEGALO VIRUS | PHARMACIA & UPJOHN COMPANY | 2001-06-26 | — | — | US | disclosed |
| US-6211376-B1 | HERPES VIRUS, CYTOMEGALO VIRUS, VARICELLA-ZOSTER VIRUS,EPSTEIN-BARR VIRUS | PHARMACIA & UPJOHN COMPANY | 2001-04-03 | — | — | US | disclosed |