Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ACP3 | P15309 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 2/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.33 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7787505 | 0.83 | MAPKAPK2 (0.34) | MAPKAPK2MEN1KMT2AACP3MAPK1 | |
| SCHEMBL7785066 | 0.83 | CRHBP (0.39) | ALDH1A1CRHBPCRHR2MAPKAPK2MEN1 | |
| SCHEMBL7787611 | 0.82 | MAPKAPK2 (0.46) | MAPKAPK2MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL7785058 | 0.82 | MAPKAPK2 (0.41) | ALDH1A1MAPKAPK2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7787494 | 0.81 | KMT2A (0.38) | ALDH1A1CRHBPCRHR2MAPKAPK2MEN1 | |
| SCHEMBL7789059 | 0.77 | MAPKAPK2 (0.49) | MAPKAPK2MEN1KMT2AMAPK1CYP3A4 | |
| SCHEMBL7780618 | 0.77 | MAPKAPK2 (0.42) | MAPKAPK2MEN1KMT2AMAPK1CYP3A4 | |
| SCHEMBL7780336 | 0.74 | MAPKAPK2 (0.41) | ALDH1A1MAPKAPK2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2770991 | 0.73 | GAA (0.47) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL7787681 | 0.72 | MAPKAPK2 (0.44) | MAPKAPK2MEN1KMT2AACP3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |