Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.63 |
| ▸ | FAAH | O00519 | 2/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.58 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.58 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | RARB | P10826 | 1/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.58 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11446179 | 0.90 | PTGS2 (0.59) | PTGS2FAAHPTGS1CXCR1CXCR2 | |
| SCHEMBL12986500 | 0.87 | FAAH (0.66) | PTGS2FAAHPTGS1CXCR1CXCR2 | |
| SCHEMBL8024626 | 0.86 | PTGS2 (0.64) | PTGS2FAAHPTGS1CXCR1CXCR2 | |
| SCHEMBL12715089 | 0.86 | PTGS2 (0.64) | PTGS2FAAHPTGS1CXCR1CXCR2 | |
| SCHEMBL12884181 | 0.86 | PTGS2 (0.64) | PTGS2FAAHPTGS1CXCR1CXCR2 | |
| SCHEMBL11572717 | 0.86 | PTGS2 (0.64) | PTGS2FAAHPTGS1CXCR1CXCR2 | |
| SCHEMBL17854658 | 0.84 | PTGS2 (0.63) | PTGS2FAAHPTGS1CXCR1CXCR2 | |
| SCHEMBL19376388 | 0.84 | PTGS2 (0.63) | PTGS2FAAHPTGS1CXCR1CXCR2 | |
| SCHEMBL12896272 | 0.83 | PTGS2 (0.66) | PTGS2FAAHPTGS1CXCR1CXCR2 | |
| SCHEMBL17464177 | 0.83 | PTGS2 (0.66) | PTGS2FAAHPTGS1CXCR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587318-A | FROM RACEMIC MIXTURES OF THE CORRESPONDING ESTER BY ENANTIOSPECIFIC HYDROLYSIS USING LIPASE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1996-12-24 | — | — | US | claimed |
| EP-0227078-A1 | Process for preparing (S)-alpha-methylarylacetic acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1987-07-01 | — | — | EP | claimed |
| EP-0759426-B1 | Process for the preparation of optically active 1-aryl-alkylamines | BAYER AG (DE) | 2001-11-28 | — | — | EP | disclosed |
| US-5773656-A | Process for the preparation of optically active 1-aryl-alkylamines | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-30 | — | — | US | disclosed |
| EP-0759426-A2 | Process for the preparation of optically active 1-aryl-alkylamines | BAYER AG (DE) | 1997-02-26 | — | — | EP | disclosed |
| WO-1995007359-A1 | A PROCESS FOR CARRYING OUT ENZYMATICALLY CATALYZED CONVERSIONS OF ORGANIC COMPOUNDS | TECHNISCHE UNIVERSITEIT DELFT (NL) | 1995-03-16 | — | — | WO | disclosed |