Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7803612 | 0.94 | TDP1 (0.45) | TDP1MEN1KMT2AKLKB1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL27530391 | 0.87 | ALDH1A1 (0.38) | SLC2A1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7787663 | 0.86 | TDP1 (0.40) | TDP1SLC2A1MEN1KMT2AKLKB1 | |
| SCHEMBL7785567 | 0.83 | TDP1 (0.42) | TDP1MEN1KMT2AKLKB1ALDH1A1 | |
| SCHEMBL7787727 | 0.80 | KMT2A (0.42) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL7795354 | 0.79 | KMT2A (0.40) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL7780576 | 0.79 | KMT2A (0.40) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL7802013 | 0.79 | KMT2A (0.40) | MEN1KMT2AALDH1A1LMNAGAA | |
| Hydrochloric Acid SCHEMBL7785515 | 0.78 | CXCR2 (0.43) | MEN1KMT2AALDH1A1LMNAGAA | |
| Hydrochloric Acid SCHEMBL7802211 | 0.78 | KMT2A (0.40) | MEN1KMT2AALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |