Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 9/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785002 | 0.95 | MAPKAPK2 (0.36) | MAPKAPK2 | |
| SCHEMBL7780418 | 0.92 | MAPKAPK2 (0.36) | MAPKAPK2POLBPTGER4 | |
| SCHEMBL7785671 | 0.92 | IDH1 (0.35) | S1PR3MAPKAPK2POLBPTGER4 | |
| SCHEMBL7780588 | 0.91 | MAPKAPK2 (0.38) | MAPKAPK2POLB | |
| Hydrochloric Acid SCHEMBL7785684 | 0.84 | RCE1 (0.42) | S1PR3PDE2APTGER4 | |
| SCHEMBL7780368 | 0.83 | MAPKAPK2 (0.43) | MAPKAPK2POLB | |
| SCHEMBL7780351 | 0.83 | MAPKAPK2 (0.43) | MAPKAPK2POLB | |
| SCHEMBL7785641 | 0.83 | MAPKAPK2 (0.36) | S1PR3MAPKAPK2POLB | |
| SCHEMBL7780392 | 0.83 | MAPKAPK2 (0.40) | S1PR3MAPKAPK2POLB | |
| SCHEMBL7787745 | 0.83 | MAPKAPK2 (0.41) | S1PR3MAPKAPK2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |