Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.53 |
| ▸ | ITGAV | P06756 | 6/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787963 | 1.00 | ITGB3 (0.53) | ITGB3ITGAVPPARGMAPTSMN1; SMN2 | |
| SCHEMBL24106585 | 0.92 | ITGB3 (0.50) | ITGB3ITGAVMAPTSMN1; SMN2KDM4E | |
| SCHEMBL7785677 | 0.89 | ITGB3 (0.51) | ITGB3ITGAVMAPTSMN1; SMN2KDM4E | |
| SCHEMBL7785678 | 0.89 | ITGB3 (0.51) | ITGB3ITGAVMAPTSMN1; SMN2KDM4E | |
| SCHEMBL28605229 | 0.87 | ITGB3 (0.51) | ITGB3ITGAVMAPTSMN1; SMN2KDM4E | |
| SCHEMBL24106581 | 0.87 | ITGB3 (0.51) | ITGB3ITGAVMAPTSMN1; SMN2KDM4E | |
| SCHEMBL31122201 | 0.87 | ITGB3 (0.51) | ITGB3ITGAVMAPTSMN1; SMN2KDM4E | |
| SCHEMBL7790192 | 0.87 | NAMPT (0.58) | ITGB3ITGAV | |
| SCHEMBL7785608 | 0.85 | NAMPT (0.57) | ITGB3ITGAVSMN1; SMN2 | |
| SCHEMBL25132977 | 0.84 | ITGB3 (0.52) | ITGB3ITGAVMAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |