Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 14/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.55 |
| ▸ | ITGAV | P06756 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785608 | 0.92 | NAMPT (0.57) | NAMPTITGB3ITGAV | |
| SCHEMBL7787963 | 0.87 | ITGB3 (0.53) | ITGB3ITGAV | |
| SCHEMBL7787965 | 0.87 | ITGB3 (0.53) | ITGB3ITGAV | |
| SCHEMBL7788366 | 0.82 | NAMPT (0.52) | NAMPTITGB3ITGAV | |
| SCHEMBL7788369 | 0.82 | NAMPT (0.52) | NAMPTITGB3ITGAV | |
| SCHEMBL7788200 | 0.81 | NAMPT (0.62) | NAMPTITGB3ITGAV | |
| SCHEMBL7788191 | 0.81 | NAMPT (0.62) | NAMPTITGB3ITGAV | |
| SCHEMBL7786259 | 0.81 | ITGB3 (0.62) | ITGB3ITGAV | |
| SCHEMBL7786264 | 0.81 | ITGB3 (0.62) | ITGB3ITGAV | |
| SCHEMBL7790196 | 0.81 | HTT (0.47) | NAMPTITGB3ITGAVHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |