Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL370440 | 0.97 | — | — | |
| SCHEMBL11229821 | 0.94 | TSHR (0.50) | TSHRTHRBALDH1A1LMNADNM1 | |
| SCHEMBL733804 | 0.94 | TSHR (0.50) | TSHRTHRBALDH1A1LMNADNM1 | |
| SCHEMBL9776618 | 0.94 | TSHR (0.50) | TSHRTHRBALDH1A1LMNADNM1 | |
| SCHEMBL6746369 | 0.94 | TSHR (0.50) | TSHRTHRBALDH1A1LMNADNM1 | |
| SCHEMBL3888791 | 0.94 | — | — | |
| SCHEMBL6748891 | 0.78 | TSHR (0.44) | ANPEPTSHRTHRBALDH1A1LMNA | |
| Hexane SCHEMBL2922117 | 0.75 | TSHR (0.58) | TSHRTHRBALDH1A1LMNATDP1 | |
| SCHEMBL6741851 | 0.75 | TSHR (0.50) | TSHRTHRBALDH1A1LMNADNM1 | |
| SCHEMBL6741870 | 0.75 | TSHR (0.50) | TSHRTHRBALDH1A1LMNADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010025005-A1 | Procatalysts, catalyst systems, and use in olefin polymerization | EASTMAN CHEMICAL COMPANY, A CORPORATION OF DELAWARE | 2001-09-27 | — | — | US | disclosed |