Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6743258 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL11594245 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL6741870 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL6748891 | 0.97 | TSHR (0.44) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL5459128 | 0.87 | ANPEP (0.47) | TSHRTHRBALDH1A1LMNASLC22A1 | |
| SCHEMBL733804 | 0.81 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL6746369 | 0.81 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL11229821 | 0.81 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL9776618 | 0.81 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| Heptane SCHEMBL6917596 | 0.79 | TSHR (0.67) | TSHRTHRBALDH1A1DNM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681978-A | Method for the stereocontrolled synthesis of stegobinone and useful borane intermediates | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1997-10-28 | — | — | US | claimed |
| US-9622479-B2 | Boron complexes with gradual 1-methylcyclopropene releasing capability | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2017-04-18 | — | — | US | disclosed |
| US-9622479-B2 | Boron complexes with gradual 1-methylcyclopropene releasing capability | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2017-04-18 | — | — | US | disclosed |
| US-9622479-B2 | Boron complexes with gradual 1-methylcyclopropene releasing capability | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2017-04-18 | — | — | US | disclosed |
| US-20150366212-A1 | Boron Complexes With Gradual 1- Methylcyclopropene Releasing Capability | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2015-12-24 | — | — | US | disclosed |
| US-20150366212-A1 | Boron Complexes With Gradual 1- Methylcyclopropene Releasing Capability | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2015-12-24 | — | — | US | disclosed |
| US-20150366212-A1 | Boron Complexes With Gradual 1- Methylcyclopropene Releasing Capability | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2015-12-24 | — | — | US | disclosed |
| US-6696380-B2 | Procatalysts, catalyst systems, and use in olefin polymerization | WESTLAKE LONGVIEW CORPORATION | 2004-02-24 | — | — | US | disclosed |
| US-6677410-B2 | COORDINATION CATALYSTS | EASTMAN CHEMICAL COMPANY | 2004-01-13 | — | — | US | disclosed |
| CN-1418227-A | Procatalyst containing bidentate ligand, catalyst system and use thereof in olefin polymerization | EASTMAN CHEM CO (US) | 2003-05-14 | — | — | CN | disclosed |
| US-20010051587-A1 | Procatalysts, catalyst systems, and use in olefin polymerization | WESTLAKE LONGVIEW CORPORATION | 2001-12-13 | — | — | US | disclosed |
| US-20010031841-A1 | Procatalysts, catalyst systems, and use in olefin polymerization | WESTLAKE LONGVIEW CORPORATION | 2001-10-18 | — | — | US | disclosed |
| US-20010029286-A1 | Procatalysts, catalyst systems, and use in OLEFIN polymerization | EASTMAN CHEMICAL COMPANY, A CORP. OF DELAWARE | 2001-10-11 | — | — | US | disclosed |
| US-20010025005-A1 | Procatalysts, catalyst systems, and use in olefin polymerization | EASTMAN CHEMICAL COMPANY, A CORPORATION OF DELAWARE | 2001-09-27 | — | — | US | disclosed |
| EP-0694549-A2 | Synthesis of organohaloboranes and alkoxyorganoboranes | Mine Safety Appliances Company (US) | 1996-01-31 | — | — | EP | disclosed |
| US-5463131-A | Synthesis of organohaloboranes and alkoxyorganoboranes | MINE SAFETY APPLIANCES COMPANY (US) | 1995-10-31 | — | — | US | disclosed |
| EP-0044835-A1 | CATALYSED ALTERNATING COPOLYMERISATION AND PRODUCT | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1982-02-03 | — | — | EP | disclosed |
| WO-1981001289-A1 | CATALYSED ALTERNATING COPOLYMERISATION AND PRODUCT | BAMFORD C | 1981-05-14 | — | — | WO | disclosed |
| US-4121032-A | Process for preparing alternating copolymer of conjugated vinyl compound and olefinic unsaturated compound with oxygen and boron compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-10-17 | — | — | US | disclosed |
| US-3989882-A | Process for preparing an alternating copolymer of a conjugated vinyl compound and an olefinic unsaturated compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150366212-A1 | Boron Complexes With Gradual 1- Methylcyclopropene Releasing Capability | BOLA2; BOLA2B, BLVRB, CBR1 | TSHR 70/4885THRB 485/4885ALDH1A1 3716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.