SCHEMBL733804

SCHEMBL733804

CCCCCCCCB(Cl)Cl

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
THRB P10828 1/20 0.50
ALDH1A1 P00352 3/20 0.45
DNM1 Q05193 7/20 0.41
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 1/20 0.38
SLC22A1 O15245 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9776618 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL11229821 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL370440 0.97
SCHEMBL7788025 0.94 ANPEP (0.43) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL11594245 0.81 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL6741851 0.81 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL6741870 0.81 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
Heptane SCHEMBL6917596 0.79 TSHR (0.67) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL6748891 0.78 TSHR (0.44) TSHRTHRBALDH1A1DNM1LMNA
Hexane SCHEMBL2922117 0.75 TSHR (0.58) TSHRTHRBALDH1A1DNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2067782-B2 HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND THEIR PRODUCTION METHODS TOSOH CORP (JP) 2018-06-27 EP disclosed
EP-2067782-B1 HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND THEIR PRODUCTION METHODS TOSOH CORP (JP) 2014-08-13 EP disclosed
US-8138355-B2 Heteroacene derivative, tetrahaloterphenyl derivative, and processes for producing the same TOSOH CORPORATION (JP) 2012-03-20 US disclosed
US-20090261300-A1 HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND PROCESSES FOR PRODUCING THE SAME TOSOH CORPORATION (JP) 2009-10-22 US disclosed
EP-2067782-A1 HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND THEIR PRODUCTION METHODS Tosoh Corporation (JP) 2009-06-10 EP disclosed
CN-1196719-C Procatalysts including bidentate ligands, catalyst systems and their use in olefin polymerization EASTMAN CHEM CO (US) 2005-04-13 CN disclosed
CN-1144821-C Procatalysts comprising bidentate ligands, catalyst systems, and use in olefin polymerization 伊斯曼化学公司 2004-04-07 CN disclosed
US-6696380-B2 Procatalysts, catalyst systems, and use in olefin polymerization WESTLAKE LONGVIEW CORPORATION 2004-02-24 US disclosed
US-6677410-B2 COORDINATION CATALYSTS EASTMAN CHEMICAL COMPANY 2004-01-13 US disclosed
CN-1416440-A Procatalysts catalyst systems, and use in olefin polymerization EASTMAN CHEM CO (US) 2003-05-07 CN disclosed
EP-0185521-A1 Polymerization catalyst, production and use EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-06-25 EP disclosed
EP-0185520-A1 Polymerization catalyst, production and use EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-06-25 EP disclosed
US-4579834-A Polymerization catalyst, production and use EXXON RESEARCH & ENGINEERING CO. (US) 1986-04-01 US disclosed
US-4578374-A Polymerization catalyst, production and use EXXON RESEARCH & ENGINEERING CO. (US) 1986-03-25 US disclosed
EP-0174102-A1 Polymerization catalyst, production and use EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-03-12 EP disclosed
EP-0174104-A1 Polymerization catalyst, production and use EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-03-12 EP disclosed
EP-0173488-A1 Polymerization catalyst, production and use EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-03-05 EP disclosed
EP-0173487-A1 Polymerization catalyst, production and use EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-03-05 EP disclosed
US-4558025-A COORDINATION CATALYST EXXON RESEARCH & ENGINEERING CO. (US) 1985-12-10 US disclosed
US-4558024-A COORDINATION CATALYST EXXON RESEARCH & ENGINEERING CO. (US) 1985-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090261300-A1 HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND PROCESSES FOR PRODUCING THE SAME AS3MT, TERT, TEAD1 TSHR 173/4885THRB 71/4885ALDH1A1 2196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.