Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 16/20 | 0.62 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.61 |
| ▸ | ITGAV | P06756 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7788191 | 1.00 | NAMPT (0.62) | NAMPTITGB3ITGAV | |
| SCHEMBL7788371 | 0.85 | ITGB3 (0.53) | ITGB3ITGAV | |
| SCHEMBL7788366 | 0.83 | NAMPT (0.52) | NAMPTITGB3ITGAV | |
| SCHEMBL7788369 | 0.83 | NAMPT (0.52) | NAMPTITGB3ITGAV | |
| SCHEMBL7790192 | 0.81 | NAMPT (0.58) | NAMPTITGB3ITGAV | |
| SCHEMBL7856514 | 0.77 | ITGB3 (0.64) | NAMPTITGB3ITGAV | |
| SCHEMBL20379734 | 0.77 | NAMPT (1.00) | NAMPT | |
| SCHEMBL30818059 | 0.77 | NAMPT (1.00) | NAMPT | |
| SCHEMBL14501730 | 0.77 | ITGB3 (0.53) | NAMPTITGB3ITGAV | |
| SCHEMBL17325743 | 0.76 | NAMPT (1.00) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |