SCHEMBL7788747

SCHEMBL7788747

O=C(O)CCC1CC(=O)OC1=S

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.41
NPSR1 Q6W5P4 1/20 0.36
HTT P42858 1/20 0.32
EGFR P00533 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7788743 0.85 FOLH1 (0.38) FOLH1NPSR1HTTEGFR
SCHEMBL2477172 0.83 FOLH1 (0.42) FOLH1NPSR1HTTKDM4E
SCHEMBL11757634 0.75 ALDH1A1 (0.39)
SCHEMBL6978155 0.73
SCHEMBL2805843 0.73 TSHR (0.39) FOLH1NPSR1
SCHEMBL11756397 0.72
SCHEMBL8405724 0.71 FOLH1 (0.48) FOLH1NPSR1HTTKDM4E
SCHEMBL14318654 0.71 FOLH1 (0.48) FOLH1NPSR1HTTKDM4E
SCHEMBL11758186 0.69 ALDH1A1 (0.49) HTT
SCHEMBL11754061 0.69 ALDH1A1 (0.49) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1157074-A1 A METHOD FOR THE ADHESION OF VINYLIDENE FLUORIDE RESINS TO METAL SUBSTRATES, AND AN ELECTRODE STRUCTURE AND ITS METHOD OF PRODUCTION ELF ATOCHEM S.A. (FR) 2001-11-28 EP disclosed
WO-2000049103-A1 A METHOD FOR THE ADHESION OF VINYLIDENE FLUORIDE RESINS TO METAL SUBSTRATES, AND AN ELECTRODE STRUCTURE AND ITS METHOD OF PRODUCTION ATOFINA (FR) 2000-08-24 WO disclosed
WO-1997049756-A1 METHOD OF BONDING HIGH MOLECULAR RESINS TO METALS ELF ATOCHEM S.A. (FR) 1997-12-31 WO disclosed