Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29603148 | 0.81 | THRB (0.46) | THRBPOLBHTTAPEX1TDP1 | |
| SCHEMBL146236 | 0.81 | THRB (0.46) | THRBPOLBHTTAPEX1TDP1 | |
| SCHEMBL20077627 | 0.81 | SMN1; SMN2 (0.42) | THRBTDP1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL7790735 | 0.79 | THRB (0.54) | THRBHTTSLC16A3L3MBTL1ALDH1A1 | |
| SCHEMBL21112016 | 0.78 | FOLH1 (0.50) | THRBPOLBHTTAPEX1TDP1 | |
| SCHEMBL28187046 | 0.78 | SCN1A (0.45) | THRBPOLBHTTAPEX1TDP1 | |
| SCHEMBL31744950 | 0.78 | TYR (0.54) | THRBPOLBHTTAPEX1TDP1 | |
| SCHEMBL716321 | 0.78 | TYR (0.54) | THRBPOLBHTTAPEX1TDP1 | |
| SCHEMBL28314143 | 0.78 | THRB (0.46) | THRBPOLBHTTAPEX1TDP1 | |
| SCHEMBL27459251 | 0.77 | KMT2A (0.44) | THRBPOLBHTTAPEX1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115298535-A | Detectable arrays for distinguishing analytes and diagnostics and methods and systems related thereto | 恩拓普斯有限公司 | 2022-11-04 | — | — | CN | claimed |
| CN-110088223-B | Sealing material | 汉高股份有限及两合公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115298535-A | Detectable arrays for distinguishing analytes and diagnostics and methods and systems related thereto | 恩拓普斯有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-108368384-B | Anaerobically curable compositions | 汉高知识产权控股有限责任公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114026190-A | Anaerobically curable compositions | 汉高知识产权控股有限责任公司 | 2022-02-08 | — | — | CN | disclosed |
| CN-113412253-A | (meth) acrylate functionalized waxes and curable compositions made therefrom | 汉高知识产权控股有限责任公司 | 2021-09-17 | — | — | CN | disclosed |
| CN-112771132-A | Anaerobically curable compositions comprising metallocene and acetophenylhydrazine curing systems | 汉高知识产权控股有限责任公司 | 2021-05-07 | — | — | CN | disclosed |
| EP-0849258-B1 | Process for the preparation of ethylenically unsaturated isocyanates | NOVARTIS AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| US-5990345-A | Process for preparation of ethylenically unsaturated isocyanates | NOVARTIS AG (CH) | 1999-11-23 | — | — | US | disclosed |
| EP-0849258-A1 | Process for the preparation of ethylenically unsaturated isocyanates | Novartis AG (CH) | 1998-06-24 | — | — | EP | disclosed |