Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29745732 | 0.79 | THRB (0.55) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL148311 | 0.79 | THRB (0.55) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL7788779 | 0.79 | THRB (0.44) | THRBTSHRALDH1A1SLC16A3LMNA | |
| SCHEMBL2320528 | 0.78 | THRB (0.58) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL30775445 | 0.77 | THRB (0.57) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL961984 | 0.77 | THRB (0.57) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL28338758 | 0.77 | THRB (0.57) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL20449043 | 0.77 | THRB (0.56) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL9819115 | 0.76 | THRB (0.55) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL7859948 | 0.76 | THRB (0.55) | THRBTSHRALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0849258-B1 | Process for the preparation of ethylenically unsaturated isocyanates | NOVARTIS AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| US-5990345-A | Process for preparation of ethylenically unsaturated isocyanates | NOVARTIS AG (CH) | 1999-11-23 | — | — | US | disclosed |
| EP-0849258-A1 | Process for the preparation of ethylenically unsaturated isocyanates | Novartis AG (CH) | 1998-06-24 | — | — | EP | disclosed |