SCHEMBL7789065

SCHEMBL7789065

CCc1ccc(/C=N/N=C/c2ccc(C(F)(F)F)c(F)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 8/20 0.41
NPFFR1 Q9GZQ6 2/20 0.37
NPFFR2 Q9Y5X5 2/20 0.37
MAOA P21397 1/20 0.36
KCNH2 Q12809 1/20 0.36
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
PKM P14618 2/20 0.35
GAA P10253 1/20 0.35
DAO P14920 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPK1 P28482 1/20 0.34
THPO P40225 1/20 0.34
CHRM5 P08912 1/20 0.34
GRM5 P41594 1/20 0.34
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7789066 1.00 KIF11 (0.41) KIF11NPFFR1NPFFR2MAOAKCNH2
SCHEMBL7791467 0.89 KIF11 (0.39) KIF11NPFFR1NPFFR2KCNH2NPC1
SCHEMBL7791462 0.89 KIF11 (0.39) KIF11NPFFR1NPFFR2KCNH2NPC1
SCHEMBL7791138 0.86 GRIN2D (0.49) KIF11NPFFR1NPFFR2KCNH2DAO
SCHEMBL7791141 0.86 GRIN2D (0.49) KIF11NPFFR1NPFFR2KCNH2DAO
SCHEMBL7793138 0.85 GRIN2D (0.45) KIF11CYP3A4CYP2D6CHRM5
SCHEMBL7793137 0.85 GRIN2D (0.45) KIF11CYP3A4CYP2D6CHRM5
SCHEMBL7791882 0.84 GRIN2D (0.44) KIF11CYP3A4CYP2D6CHRM5
SCHEMBL7791880 0.84 GRIN2D (0.44) KIF11CYP3A4CYP2D6CHRM5
SCHEMBL7793400 0.84 MAOA (0.37) MAOAKCNH2NPC1RAB9APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed