Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 18/20 | 0.74 |
| ▸ | ALOX5 | P09917 | 10/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796089 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1ALOX5 | |
| SCHEMBL6671775 | 0.85 | PTGS2 (0.71) | PTGS2PTGS1ALOX5 | |
| SCHEMBL6669025 | 0.83 | PTGS2 (0.76) | PTGS2PTGS1ALOX5 | |
| SCHEMBL6671305 | 0.83 | PTGS2 (0.68) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4614280 | 0.80 | PTGS2 (0.81) | PTGS2PTGS1ALOX5 | |
| SCHEMBL8106974 | 0.75 | PTGS2 (0.57) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7564450 | 0.74 | PTGS2 (0.67) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4612949 | 0.73 | PTGS2 (1.00) | PTGS2PTGS1ALOX5 | |
| SCHEMBL3483031 | 0.73 | GAA (0.66) | — | |
| SCHEMBL7799590 | 0.72 | PTGS2 (0.73) | PTGS2PTGS1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0779886-B1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIV VANDERBILT (US) | 2001-12-05 | — | — | EP | disclosed |
| US-5684002-A | FOR TREATING ARTHRITIS | THE PROCTER & GAMBLE COMPANY (US) | 1997-11-04 | — | — | US | disclosed |
| EP-0779886-A1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1997-06-25 | — | — | EP | disclosed |
| WO-1996007651-A1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |